研究報告 2025
| 原著論文 |
| Liu, S., Mohri, S., Tsukamoto, M., Yanai, Y., Manabe, Y., Sugawara, T. Preventive effects of dietary fucoxanthin on UVA-induced photoaging in hairless mice. Journal of the Science of Food and Agriculture, 105, 453-464, 2025. https://doi.org/10.1002/jsfa.13842 |
| Yamasaki, H., Ogawa, T., Manabe, Y., Sugawara, T., Tani, F. Development of decolorization and degreasing reagents for optical clearing that enables visualization of the three-dimensional microstructure inside foods. Journal of Food Composition and Analysis, 137(Part B), 106956, 2025. https://doi.org/10.1016/j.jfca.2024.106956 |
| Liu, S., Manabe, Y., Sugawara, T.
Oral administration of astaxanthin mitigates chronological skin aging in
mice.
Bioscience, Biotechnology, and Biochemistry, 89, 612-621, 2025. https://doi.org/10.1093/bbb/zbae205
|
| Manabe, Y., Nitta, T., Ichihara, M., Maoka, T., Sugawara, T. Dehydrometabolites of siphonaxanthin, a carotenoid from green algae, suppress TLR1/2-induced inflammatory response more strongly than siphonaxanthin. Journal of Biological Chemistry, 301, 108246, 2025. https://doi.org/10.1016/j.jbc.2025.108246 |
| Zheng J., Manabe Y., Sugawara T.
Preventive effect of siphonaxanthin, a carotenoid from green algae, against
diabetic nephropathy and lipid metabolism insufficiency in skeletal muscle.
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1870, 159604, 2025. https://doi.org/10.1016/j.bbalip.2025.159604
|
| Kato, Y., Manabe, Y., Inoue, N., Nagao, K., Nagai, T., Sugawara, T., Anti-inflammatory function of ozonated ethyl ester of unsaturated fatty acids. Journal of Oleo Sciences, 74, 495-501, 2025. https://doi.org/10.5650/jos.ess25040 |
| Wakuda, N., Manabe, Y., Seko, T., Sugawara, T. Different suppressive effects of canthaxanthin and fucoxanthin on cellular responses of human dermal fibroblasts to Ultraviolet A irradiation. Bioscience, Biotechnology, and Biochemistry, 89, 1038-1044, 2025. https://doi.org/10.1093/bbb/zbaf056 |
| Manabe, Y., Ueda, M., Sugawara, T. β-Carotene suppresses lipopolysaccharide-induced nitric oxide production in microglia via retinoic acid receptor-dependent mechanism. Journal of Oleo Science, 74, 845-857, 2025. https://doi.org/10.5650/jos.ess25072 |
| Kavalappa, Y.P., Stephen, N.M., Jayalakshmi, B.K., Sugawara, T., Manabe, Y., Hirata, T., Ponesakki, G. Siphonaxanthin inhibits the growth of breast cancer cell subtypes by modulating the expression of cellular proteins associated with antioxidant defence, cell survival and apoptosis signaling. Medical Oncology, 42, 259, 2025. https://doi.org/10.1007/s12032-025-02798-y |
| Tsuzuki, S., Yamasaki, M., Sugawara, T., Manabe Y., Toyoda, M., Mizutani, K., Sasaki, T. Fatty amines and 1-monoglycerides with cytotoxic activity serve as ligands for a multipurpose receptor CD36. Biomedical Research, 46, 189-202, 2025. https://doi.org/10.2220/biomedres.46.189 |
| 著書・総説など |
| Manabe, Y., Sugawara, T., Potential of siphonaxanthin, a green algal carotenoid, to prevent obesity and related diseases. Journal of Natural Medicines, accepted for publication. https://doi.org/10.1007/s11418-025-01897-4 |
| 菅原達也, 食品スフィンゴ脂質の健康機能性, オレオサイエンス, 25, 389-396, 2025. https://doi.org/10.5650/oleoscience.25.389 |
| 真鍋祐樹, カロテノイドの代謝変換研究, 化学と生物, 63, 398-400, 2025. |
| 真鍋祐樹, マリンカロテノイドの生体内代謝と生物活性(機能性), http://www.mac.or.jp/mail/251001/01.shtml |