研究報告 2025


原著論文
Liu, S., Mohri, S., Tsukamoto, M., Yanai, Y., Manabe, Y., Sugawara, T.
Preventive effects of dietary fucoxanthin on UVA-induced photoaging in hairless mice.
Journal of the Science of Food and Agriculture, 105, 453-464, 2025. https://doi.org/10.1002/jsfa.13842
Yamasaki, H., Ogawa, T., Manabe, Y., Sugawara, T., Tani, F.
Development of decolorization and degreasing reagents for optical clearing that enables visualization of the three-dimensional microstructure inside foods.
Journal of Food Composition and Analysis,
137(Part B), 106956, 2025. https://doi.org/10.1016/j.jfca.2024.106956
Liu, S., Manabe, Y., Sugawara, T.
Oral administration of astaxanthin mitigates chronological skin aging in mice.
Bioscience, Biotechnology, and Biochemistry, 89, 612-621, 2025. https://doi.org/10.1093/bbb/zbae205
Manabe, Y., Nitta, T., Ichihara, M., Maoka, T., Sugawara, T.
Dehydrometabolites of siphonaxanthin, a carotenoid from green algae, suppress TLR1/2-induced inflammatory response more strongly than siphonaxanthin.
Journal of Biological Chemistry, 301, 108246, 2025. https://doi.org/10.1016/j.jbc.2025.108246
Zheng J., Manabe Y., Sugawara T.
Preventive effect of siphonaxanthin, a carotenoid from green algae, against diabetic nephropathy and lipid metabolism insufficiency in skeletal muscle.
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1870, 159604, 2025. https://doi.org/10.1016/j.bbalip.2025.159604
Kato, Y., Manabe, Y., Inoue, N., Nagao, K., Nagai, T., Sugawara, T.,
Anti-inflammatory function of ozonated ethyl ester of unsaturated fatty acids.
Journal of Oleo Sciences,
74, 495-501, 2025. https://doi.org/10.5650/jos.ess25040
Wakuda, N., Manabe, Y., Seko, T., Sugawara, T.
Different suppressive effects of canthaxanthin and fucoxanthin on cellular responses of human dermal fibroblasts to Ultraviolet A irradiation.
Bioscience, Biotechnology, and Biochemistry, 89, 1038-1044, 2025. https://doi.org/10.1093/bbb/zbaf056
 Manabe, Y., Ueda, M., Sugawara, T.  
β-Carotene suppresses lipopolysaccharide-induced nitric oxide production in microglia via retinoic acid receptor-dependent mechanism.
Journal of Oleo Science, accepted.



著書・総説など
Manabe, Y., Sugawara, T.,
Potential of siphonaxanthin, a green algal carotenoid, to prevent obesity and related diseases.
Journal of Natural Medicines, accepted for publication. https://doi.org/10.1007/s11418-025-01897-4