研究報告 2015





原著論文


Nanthirudjanar T, Furumoto H, Zheng J, Kim YI1, Goto T, Takahashi N, Kawada T, Park SB, Hirata A, Kitamura N, Kishino S, Ogawa J, Hirata T, Sugawara T. Gut microbial fatty acid metabolites reduce triacylglycerol levels in hepatocytes. Lipids, 50, 1093-1102, 2015.


Oba C, Morifuji M, Ichikawa S, Ito K , Kawahata K, Itou H, Sugawara T. Dietary milk sphingomyelin prevents disruption of skin barrier function in hairless mice after UV-B irradiation. PLOS ONE, 10, e0136377, 2015.


Nishikawa Y, Furukawa A , Shiga I, Muroi Y, Ishii T, Hongo Y, Takahashi S, Sugawara T, Koshino H, Ohnishi M. Cytoprotective Effects of Lysophospholipids from Sea Cucumber Holothuria atra. PLOS ONE, 10, e0135701, 2015.


Morifuji M, Higashi S, Oba C, Ichikawa S, Kawahata K, Yamaji T, Itoh H, Manabe Y,
Sugawara T. Milk phospholipids enhance lymphatic absorption of dietary sphingomyelin in lymph-cannulated rats. Lipids, 50, 987-96, 2015.


Hyodo K, Taniguchi T, Manabe Y, Kaido M, Mise K, Sugawara T, Taniguchi H, Okuno T. Phosphatidic acid produced by phospholipase D promotes RNA replication of a plant RNA virus. PLOS Pathogens, 11, e1004909, 2015.


Cong PX, Gao RC, Xue CH, Li ZJ, Zhang HW, Khan MN, Xue Y,Sugawara T, Xu J. Molecular species analysis of monosialogangliosides from sea urchin Strongylocentrotus nudus by RPLC-ESI-MS/MS. Food Chemistry, 166, 473-478, 2015.


Li Z, K Noda, E Fujita, Y Manabe, T Hirata, T Sugawara. The green algal carotenoid siphonaxanthin inhibits adipogenesis in 3T3-L1 preadipocytes and the accumulation of lipids in white adipose tissue of KK-Ay mice. Journal of Nutrition, 145, 490-498, 2015.


Jia Z, S Li, P Cong, Y Wang, T Sugawara, C Xue, J Xu. High throughput analysis of cerebrosides from the sea cucumber pearsonothria graeffei by liquid chromatography-quadrupole-time-of-flight mass spectrometry. Journal of Oleo Sciences, 64, 51-60, 2015.


Goto T, Kim YIl,Furuzono T, Takahashi N, Yamakuni K, Yang HE, Li Y, Ohue R,
Nomura W, T Sugawara, R Yu,Kitamura N,Park SB, Kishino S, Ogawa J, Kawada T. 10-oxo-12(Z)-octadecenoic acid, a linoleic acid metabolite produced by gut lactic acid bacteria, potently activates PPARgamma and stimulates adipogenesis. Biochemical and Biophysical Research Communications, 459, 597-603, 2015.


Morifuji M,Oba C, Ichikawa S, Ito K,Kawahata K, Asami Y, Ikegami S, Itou H,
and Sugawara T. A novel mechanism for improvement of dry skin by dietary milk phospholipids. Effect on epidermal covalently-bound ceramides and skin inflammation in hairless mice. Journal of Dermatological Science. 78, 224-231, 2015 .


Arunkumar R, Prashanth KV, Manabe Y, Hirata T, Sugawara T, Dharmesh SM, Baskaran V. Biodegradable poly (lactic-co-glycolic acid)‐polyethylene glycol nanocapsules. an efficient carrier for improved solubility, bioavailability, and anticancer property of lutein.
Journal of Pharmaceutical Sciences. 104, 2085-2093, 2015.







著書・総説等


菅原達也、真鍋祐樹. 第4編アレルギー対策食品・素材の開発第1章抗アレルギー食品・素材12.海藻カロテノイド. 
食物アレルギーの現状とリスク低減化食品素材の開発.
(森山達哉,穐山浩 監修)シーエムシー出版,  222-226, 2015.



Niranjana R, Gayathri R, Stephen Nimish Mol, Sugawara T, Hirata T, Miyashita K, Ganesan P. Carotenoids modulate the hallmarks of cancer cells. Journal of Functional Foods, 18, 968-985, 2015.


菅原達也: 皮膚に対する作用に注目した食品機能成分の評価. Trace Nutrients Research (微量栄養素研究) 32, 72-77, 2015